MolNFT v1 · #139028 · protein
Crystal structure of EGFR 696-1022 T790M in complex with WZ4003
5X2K: “Crystal structure of EGFR 696-1022 T790M in complex with WZ4003”. X-ray diffraction, 1 ligand (0UN). MolNFT v1 #139028 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5X2K
- Type
- protein
- Length
- 314 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P00533
- Ligands
- 0UN
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 314 | — | P00533 |
Ligands and binding sites
- 0UN · N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5X2K · Crystal structure of EGFR 696-1022 T790M in complex with WZ4003 · the same entry in another collection · chain A against A, TM-score 1.00
- P00533 · AlphaFold monomer V2.0 prediction for epidermal growth factor receptor (P00533) · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00533
- Elsewhere: RCSB PDB 5X2K · PDBe 5X2K · UniProt P00533
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