MolNFT v1 · #139004 · protein
Structure of the cytosolic domain of dotm derived from legionella pneumophila
5X1U · Uncharacterized protein: “Structure of the cytosolic domain of dotm derived from legionella pneumophila”. X-ray diffraction, 3 pockets (best druggability 0.37). MolNFT v1 #139004 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5X1U
- Type
- protein
- Length
- 398 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- Q5WZ95
- Pockets
- 3 · best druggability 0.37
Structure
x-ray diffraction · 2 distinct chains · 63% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein | protein | 190 | 65% helix, 2% strand | Q5WZ95 |
| B | Uncharacterized protein | protein | 208 | 61% helix, 2% strand | Q5WZ95 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 53 | 0.37 | 0.79 | 15 | empty |
| 2 | 78 | 0.35 | 0.75 | 19 | empty |
| 3 | 65 | 0.29 | 0.74 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 715 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 17 modified (engineered).
Compared structures
- 5X1U · Structure of the cytosolic domain of DotM derived from Legionella pneumophila · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5WZ95
- Elsewhere: RCSB PDB 5X1U · PDBe 5X1U · UniProt Q5WZ95
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