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Structure of the cytosolic domain of dotm derived from legionella pneumophila

Analyse Structure of the cytosolic domain of dotm derived from legionella pneumophila in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5X1U
Type: protein
Length: 398 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized protein
UniProt: Q5WZ95
Pockets: 3 · best druggability 0.37

Structure

x-ray diffraction · 2 distinct chains · 63% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized protein	protein	190	65% helix, 2% strand	Q5WZ95
B	Uncharacterized protein	protein	208	61% helix, 2% strand	Q5WZ95

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.37	0.79	15	empty
2	78	0.35	0.75	19	empty
3	65	0.29	0.74	14	empty

Interfaces

1 interface between chains.

A–B · 715 Å² buried · 10 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 17 modified (engineered).

Compared structures

5X1U · Structure of the cytosolic domain of DotM derived from Legionella pneumophila · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5WZ95
Elsewhere: RCSB PDB 5X1U · PDBe 5X1U · UniProt Q5WZ95

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