MolNFT v1 · #138962 · protein
Free serine kinase (E30Q mutant) in complex with phosphoserine and AMP
5X0J: “Free serine kinase (E30Q mutant) in complex with phosphoserine and AMP”. X-ray diffraction, 3 ligands (AMP, SEP, MG), 2 pockets (best druggability 0.70). MolNFT v1 #138962 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5X0J
- Type
- protein
- Length
- 241 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Free serine kinase
- UniProt
- Q5JD03
- Ligands
- AMP, SEP, MG
- Pockets
- 2 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Free serine kinase | protein | 241 | 34% helix, 27% strand | Q5JD03 |
Ligands and binding sites
- AMP · Adenosine monophosphate · ligand · chains A
- SEP · Phosphoserine · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 508 | 0.70 | 0.80 | 47 | AMP, SEP, MG |
| 2 | 84 | 0.35 | 0.75 | 16 | empty |
Compared structures
- 5X0J · Free serine kinase (E30Q mutant) in complex with phosphoserine and AMP · the same entry in another collection · chain A against A, TM-score 1.00
- Q5JD03 · AlphaFold monomer V2.0 prediction for L-serine kinase serk (Q5JD03) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5JD03
- Elsewhere: RCSB PDB 5X0J · PDBe 5X0J · UniProt Q5JD03
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