MolNFT v1 · #138946 · protein
Structural basis for a pentacyclic oleanane-type triterpenoid as a ligand of fxr
5WZX: “Structural basis for a pentacyclic oleanane-type triterpenoid as a ligand of fxr”. X-ray diffraction, 1 ligand (7VX). MolNFT v1 #138946 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5WZX
- Type
- protein
- Length
- 445 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q96RI1, Q15596
- Ligands
- 7VX
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 210 | — | Q96RI1 |
| B | — | protein | 212 | — | Q96RI1 |
| C | — | protein | 12 | — | Q15596 |
| D | — | protein | 11 | — | Q15596 |
Ligands and binding sites
- 7VX · (4ar,6ar,6as,6bs,8as,9r,12ar,14br)-2,2,6A,6B,9,12A-hexamethyl-10-oxidanylidene-1,3,4,5,6,6A,7,8,8A,9,11, 12,13,14B-tetradecahydropicene-4A-carboxylic acid · ligand · 2 copies · chains A, B
- BU3 · (R,R)-2,3-butanediol · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5WZX · Structural basis for a pentacyclic oleanane-type triterpenoid as a ligand of FXR · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96RI1
- Every structure of UniProt Q15596
- Elsewhere: RCSB PDB 5WZX · PDBe 5WZX · UniProt Q96RI1 · UniProt Q15596
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