MolNFT v1 · #138357 · protein
Estrogen receptor alpha ligand binding domain in complex with estradiol and SRC2-BCP1
5WGQ: “Estrogen receptor alpha ligand binding domain in complex with estradiol and SRC2-BCP1”. X-ray diffraction, 3 ligands (ACE, EST, NH2). MolNFT v1 #138357 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5WGQ
- Type
- protein
- Length
- 481 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03372
- Ligands
- ACE, EST, NH2
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 231 | — | P03372 |
| B | — | protein | 229 | — | P03372 |
| E | — | protein | 11 | — | — |
| F | — | protein | 10 | — | — |
Ligands and binding sites
- ACE · Acetyl group · ligand · 2 copies · chains E, F
- EST · Estradiol · ligand · 2 copies · chains A, B
- NH2 · Amino group · ion · chains B, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5WGQ · Estrogen Receptor Alpha Ligand Binding Domain in Complex with Estradiol and SRC2-BCP1 · the same entry in another collection · chain A against A, TM-score 1.00
- P03372 · AlphaFold monomer V2.0 prediction for estrogen receptor (P03372) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03372
- Elsewhere: RCSB PDB 5WGQ · PDBe 5WGQ · UniProt P03372
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