Acetolactate synthase from klebsiella pneumoniae in complex with a reaction intermediate

Structure

x-ray diffraction · 2 distinct chains.

Ligands and binding sites

• A4Y · (2S,3S)-2,3-dihydroxy-3-[(7s,8r,9as)-8-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2,7-dimethyl-5,7,8,10-tetrahydro-9AH-pyrimido[4,5-D][1, 3]thiazolo[3,2-a]pyrimidin-9A-yl]-2-methylbutanoic acid · ligand · 2 copies · chains A, B
• PYR · Pyruvic acid · ligand · 2 copies · chains A, B
• MG · Magnesium ion · metal · 6 copies · chains A, B
• PO4 · Phosphate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 5WDG · Acetolactate Synthase from Klebsiella pneumoniae in Complex with a Reaction Intermediate · the same entry in another collection · chain A against A, TM-score 1.00
• P27696 · AlphaFold monomer V2.0 prediction for acetolactate synthase, catabolic (P27696) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P27696
• Elsewhere: RCSB PDB 5WDG · PDBe 5WDG · UniProt P27696