UniProt P27696
Acetolactate synthase, catabolic (P27696)
Acetolactate synthase, catabolic (UniProt P27696), EC 2.2.1.6: 12 experimental structures on GenesisL1, 7 ligands bound, 11 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P27696
- Protein
- Acetolactate synthase, catabolic
- EC
- 2.2.1.6
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 11 · 1 record with a druggable one
Structures
12 records of P27696 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1OZF | The crystal structure of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactors | x-ray diffraction | A, B | — | — |
| 1OZF | The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactors | x-ray diffraction | A, B | — | — |
| 1OZG | The crystal structure of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and… | x-ray diffraction | A, B | — | — |
| 1OZG | The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and… | x-ray diffraction | A, B | — | — |
| 1OZH | The crystal structure of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and… | x-ray diffraction | A, B, C, D | — | — |
| 1OZH | The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and… | x-ray diffraction | A, B, C, D | — | — |
| 5D6R | Acetolactate synthase from klebsiella pneumoniae in complex with mechanism-based inhibitor | x-ray diffraction | B, M | — | — |
| 5DX6 | Acetolactate Synthase from Klebsiella pneumoniae soaked with beta-fluoropyruvate | x-ray diffraction | A, B | PO4, MG, 5GY, TPP, 65S | — |
| 5DX6 | Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate | x-ray diffraction | A, B | — | — |
| 5WDG | Acetolactate Synthase from Klebsiella pneumoniae in Complex with a Reaction Intermediate | x-ray diffraction | A, B | MG, PO4, A4Y, PYR | 11 (best 0.70) |
| 5WDG | Acetolactate synthase from klebsiella pneumoniae in complex with a reaction intermediate | x-ray diffraction | A, B | MG, PO4, A4Y, PYR | — |
| P27696 | AlphaFold monomer V2.0 prediction for acetolactate synthase, catabolic (P27696) | — | — | — |
Ligands
- MG · Magnesium ion · in 3 records
- PO4 · Phosphate ion · in 3 records
- A4Y · (2S,3S)-2,3-dihydroxy-3-[(7s,8r,9as)-8-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2,7-dimethyl-5,7,8,10-tetrahydro-9AH-pyrimido[4,5-D][1, 3]thiazolo[3,2-a]pyrimidin-9A-yl]-2-methylbutanoic acid · in 2 records
- PYR · Pyruvic acid · in 2 records
- 5GY · 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-[(1R)-2-fluoro-1-hydroxyethyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium · in 1 record
- 65S · 3-fluoro-2-oxopropanoic acid · in 1 record
- TPP · Thiamine diphosphate · in 1 record
Elsewhere
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