MolNFT v1 · #138189 · protein
Crystal structure of the epidermal growth factor receptor extracellular region in complex with epigen
5WB8: “Crystal structure of the epidermal growth factor receptor extracellular region in complex with epigen”. X-ray diffraction, 3 ligands (NAG, BMA, MAN). MolNFT v1 #138189 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5WB8
- Type
- protein
- Length
- 1,073 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P00533, Q6UW88
- Ligands
- NAG, BMA, MAN
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 501 | — | P00533 |
| B | — | protein | 32 | — | Q6UW88 |
| C | — | protein | 36 | — | Q6UW88 |
| D | — | protein | 504 | — | P00533 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 12 copies · chains A, D, B
- BMA · beta-D-mannopyranose · sugar · 3 copies
- MAN · alpha-D-mannopyranose · sugar · chains D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5WB8 · Crystal structure of the epidermal growth factor receptor extracellular region in complex… · the same entry in another collection · chain D against D, TM-score 1.00
- Q6UW88 · AlphaFold monomer V2.0 prediction for epigen (Q6UW88) · a predicted model of the same protein · chain C against A, TM-score 0.88
- P00533 · AlphaFold monomer V2.0 prediction for epidermal growth factor receptor (P00533) · a predicted model of the same protein · chain A against A, TM-score 0.69
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00533
- Every structure of UniProt Q6UW88
- Elsewhere: RCSB PDB 5WB8 · PDBe 5WB8 · UniProt P00533 · UniProt Q6UW88
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