MolNFT v1 · #138182 · protein
Ligand-free US28 with stabilizing intracellular nanobody
5WB1 · Envelope protein US28, nanobody 7 fusion protein: “Ligand-free US28 with stabilizing intracellular nanobody”. X-ray diffraction, 4 pockets (best druggability 0.83). MolNFT v1 #138182 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5WB1
- Type
- protein
- Length
- 420 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Envelope protein US28, nanobody 7 fusion protein
- UniProt
- Q80KM9
- Pockets
- 4 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 54% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Envelope protein US28, nanobody 7 fusion protein | protein | 420 | 54% helix, 15% strand | Q80KM9 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 899 | 0.83 | 0.84 | 66 | empty |
| 2 | 74 | 0.74 | 0.98 | 31 | empty |
| 3 | 262 | 0.52 | 0.75 | 26 | empty |
| 4 | 73 | 0.39 | 0.78 | 15 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 5WB1 · Ligand-free US28 with stabilizing intracellular nanobody · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q80KM9
- Elsewhere: RCSB PDB 5WB1 · PDBe 5WB1 · UniProt Q80KM9
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