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Ligand-free US28 with stabilizing intracellular nanobody

Analyse Ligand-free US28 with stabilizing intracellular nanobody in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5WB1
Type
protein
Length
420 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Envelope protein US28, nanobody 7 fusion protein
UniProt
Q80KM9
Pockets
4 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 54% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AEnvelope protein US28, nanobody 7 fusion proteinprotein42054% helix, 15% strandQ80KM9

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18990.830.8466empty
2740.740.9831empty
32620.520.7526empty
4730.390.7815empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

  • 5WB1 · Ligand-free US28 with stabilizing intracellular nanobody · the same entry in another collection · chain A against A, TM-score 1.00

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