MolNFT v1 · #138081 · protein
Crystal structure of fha domain of human aplf
5W7W · Aprataxin and pnk-like factor: “Crystal structure of fha domain of human aplf”. X-ray diffraction, 1 ligand (NA), 1 pocket (best druggability 0.53). MolNFT v1 #138081 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5W7W
- Type
- protein
- Length
- 209 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aprataxin and pnk-like factor
- EC
- 4.2.99.18
- UniProt
- Q8IW19
- Ligands
- NA
- Pockets
- 1 · best druggability 0.53
Structure
x-ray diffraction · 2 distinct chains · 0% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| T | Aprataxin and pnk-like factor (EC 4.2.99.18) | protein | 105 | 0% helix, 45% strand | Q8IW19 |
| A | Aprataxin and pnk-like factor (EC 4.2.99.18) | protein | 104 | 0% helix, 41% strand | Q8IW19 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 285 | 0.53 | 0.75 | 30 | empty |
Interfaces
1 interface between chains.
- T–A · 315 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IW19
- Elsewhere: RCSB PDB 5W7W · PDBe 5W7W · UniProt Q8IW19
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