MolNFT v1 · #137510 · protein
Crystal structure of HIV-1 reverse transcriptase (Y181C) variant in complex with N-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin- 1(2H)-YL)ETHOXY)PHENOXY)-4-methylnaphthalen-1-yl)-2-fluoro-N- methylacetamide (JLJ683), a non-nucleoside inhibitor
5VQU: “Crystal structure of HIV-1 reverse transcriptase (Y181C) variant in complex with…”. X-ray diffraction, 2 ligands (9JP, SO4). MolNFT v1 #137510 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5VQU
- Type
- protein
- Length
- 948 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03366
- Ligands
- 9JP, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 547 | — | P03366 |
| B | — | protein | 401 | — | P03366 |
Ligands and binding sites
- 9JP · N-(6-cyano-3-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}-4-methylnaphthalen-1-yl)-2-fluoro-N-methylacetamide · ligand · chains A
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5VQU · Crystal Structure of HIV-1 Reverse Transcriptase (Y181C) Variant in Complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03366
- Elsewhere: RCSB PDB 5VQU · PDBe 5VQU · UniProt P03366
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