MolNFT v1 · #137130 · protein
Human cytochrome P450 3A5 (CYP3A5)
5VEU: “Human cytochrome P450 3A5 (CYP3A5)”. X-ray diffraction, 2 ligands (HEM, RIT). MolNFT v1 #137130 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5VEU
- Type
- protein
- Length
- 5,487 residues
- Chains
- 12
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P20815
- Ligands
- HEM, RIT
Structure
x-ray diffraction · 10 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 462 | — | P20815 |
| B, J | — | protein | 458 | — | P20815 |
| C | — | protein | 469 | — | P20815 |
| D, H | — | protein | 459 | — | P20815 |
| E | — | protein | 441 | — | P20815 |
| F | — | protein | 456 | — | P20815 |
| G | — | protein | 455 | — | P20815 |
| I | — | protein | 464 | — | P20815 |
| K | — | protein | 458 | — | P20815 |
| L | — | protein | 448 | — | P20815 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · 12 copies · chains A, B, C, D, E, F, G, H, I, J, K, L
- RIT · Ritonavir · ligand · 3 copies · chains A, B, H
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5VEU · Human Cytochrome P450 3A5 (CYP3A5) · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P20815
- Elsewhere: RCSB PDB 5VEU · PDBe 5VEU · UniProt P20815
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