MolNFT v1 · #136910 · protein

PCNA mutant D41A/D42A protein defective in gene silencing

5V7K · Proliferating cell nuclear antigen: “PCNA mutant D41A/D42A protein defective in gene silencing”. X-ray diffraction, 1 pocket (best druggability 0.37). MolNFT v1 #136910 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5V7K
Type: protein
Length: 255 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Proliferating cell nuclear antigen
UniProt: P15873
Pockets: 1 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Proliferating cell nuclear antigen	protein	255	18% helix, 45% strand	P15873

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	68	0.37	0.78	16	empty

Compared structures

5V7K · PCNA mutant D41A/D42A Protein Defective in Gene Silencing · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P15873
Elsewhere: RCSB PDB 5V7K · PDBe 5V7K · UniProt P15873

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