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PCNA mutant D41A/D42A protein defective in gene silencing

Analyse PCNA mutant D41A/D42A protein defective in gene silencing in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5V7K
Type
protein
Length
255 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Proliferating cell nuclear antigen
UniProt
P15873
Pockets
1 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 45% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProliferating cell nuclear antigenprotein25518% helix, 45% strandP15873

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1680.370.7816empty

Compared structures

  • 5V7K · PCNA mutant D41A/D42A Protein Defective in Gene Silencing · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

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