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MolNFT v1 · #136806 · protein

Crystal structure of the protein of unknown function of the conserved rid protein family yyfb from yersinia pestis

5V4F · Putative translational inhibitor protein: “Crystal structure of the protein of unknown function of the conserved rid protein family yyfb from yersinia…”. X-ray diffraction, 4 pockets (best druggability 0.68). MolNFT v1 #136806 on…

PDB
5V4F
Type
protein
Length
266 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Putative translational inhibitor protein
UniProt
Q7CGF8
Pockets
4 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BPutative translational inhibitor proteinprotein13329% helix, 30% strandQ7CGF8

Ligands and binding sites

  • GOL · Glycerol · additive · 12 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12000.680.8635empty
2810.330.7420empty
3770.290.7321empty
4610.270.7319empty

Interfaces

1 interface between chains.

  • A–B · 823 Ų buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

  • 5V4F · Crystal Structure of the Protein of Unknown Function of the Conserved Rid Protein Family… · the same entry in another collection · chain A against A, TM-score 1.00

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