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Crystal structure of the protein of unknown function of the conserved rid protein family yyfb from yersinia pestis

Analyse Crystal structure of the protein of unknown function of the conserved rid… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5V4F
Type
protein
Length
266 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Putative translational inhibitor protein
UniProt
Q7CGF8
Pockets
4 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BPutative translational inhibitor proteinprotein13329% helix, 30% strandQ7CGF8

Ligands and binding sites

  • GOL · Glycerol · additive · 12 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12000.680.8635empty
2810.330.7420empty
3770.290.7321empty
4610.270.7319empty

Interfaces

1 interface between chains.

  • A–B · 823 Ų buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

  • 5V4F · Crystal Structure of the Protein of Unknown Function of the Conserved Rid Protein Family… · the same entry in another collection · chain A against A, TM-score 1.00

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