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MolNFT v1 · #136352 · protein

Insulin with proline analog fzp at position B28 in the R6 state

5UQA: “Insulin with proline analog fzp at position B28 in the R6 state”. X-ray diffraction, 5 ligands (IPH, ACN, NA). MolNFT v1 #136352 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5UQA
Type
protein
Length
297 residues
Chains
12
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P01308
Ligands
IPH, ACN, NA, ZN, CL

Structure

x-ray diffraction · 5 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, C, E, G, I, K—protein21—P01308
B—protein30—P01308
D, H, J—protein28—P01308
F—protein28—P01308
L—protein29—P01308

Ligands and binding sites

  • IPH · Phenol · ligand · 6 copies · chains A, B, F, C, D, L, E, J, G, H, I, K
  • ACN · Acetone · ligand · chains L
  • NA · Sodium ion · metal · 6 copies · chains E, F, J, K
  • ZN · Zinc ion · metal · 2 copies · chains B, F, J, D, H, L
  • CL · Chloride ion · ion · 2 copies · chains B, F, J, D, H, L
  • GOL · Glycerol · additive

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5UQA · Insulin with proline analog FzP at position B28 in the R6 state · the same entry in another collection · chain L against L, TM-score 1.00

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