MolNFT v1 · #136303 · protein + DNA
Crystal structure of the prototype foamy virus intasome with a 2- pyridinone aminal inhibitor (compound 31)
5UOQ: “Crystal structure of the prototype foamy virus intasome with a 2- pyridinone aminal inhibitor (compound 31)”. X-ray diffraction, 4 ligands (8G1, MG, ZN). MolNFT v1 #136303 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5UOQ
- Type
- protein + DNA
- Length
- 588 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P14350
- Ligands
- 8G1, MG, ZN, SO4
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 368 | — | P14350 |
| B | — | protein | 184 | — | P14350 |
| C | — | dna | 19 | — | — |
| D | — | dna | 17 | — | — |
Ligands and binding sites
- 8G1 · (3R)-8-[(3-chloro-4-fluorophenyl)methyl]-6-hydroxy-1,5, 7-trioxo-1,2',3',5,7,8,9,10-octahydro-2H-spiro[imidazo[5,1-a][2,6]naphthyridine-3,1'-indene]-7'-carbonitrile · ligand · chains A, C, D
- MG · Magnesium ion · metal · 3 copies · chains A, B
- ZN · Zinc ion · metal · chains A
- SO4 · Sulfate ion · ion · 3 copies · chains A, B
- GOL · Glycerol · additive · 5 copies · chains A, D, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5UOQ · Crystal structure of the prototype foamy virus intasome with a 2- pyridinone aminal… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14350
- Elsewhere: RCSB PDB 5UOQ · PDBe 5UOQ · UniProt P14350
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