MolNFT v1 · #136283 · protein
Structure of human neuronal nitric oxide synthase heme domain in complex with 7-[(3-ethyl-5-((METHYLAMINO)METHYL)PHENOXY) METHYL]QUINOLIN-2-amine
5UO2: “Structure of human neuronal nitric oxide synthase heme domain in complex with…”. X-ray diffraction, 4 ligands (HEM, H4B, 8J4). MolNFT v1 #136283 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5UO2
- Type
- protein
- Length
- 825 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P29475
- Ligands
- HEM, H4B, 8J4, ZN
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 416 | — | P29475 |
| B | — | protein | 409 | — | P29475 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B
- H4B · 5,6,7,8-tetrahydrobiopterin · ligand · 2 copies · chains A, B
- 8J4 · 7-({3-ethyl-5-[(methylamino)methyl]phenoxy}methyl) quinolin-2-amine · ligand · 2 copies · chains A, B
- ZN · Zinc ion · metal · chains A, B
- GOL · Glycerol · additive · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5UO2 · Structure of human neuronal nitric oxide synthase heme domain in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29475
- Elsewhere: RCSB PDB 5UO2 · PDBe 5UO2 · UniProt P29475
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