MolNFT v1 · #136207 · protein
HIV-1 wild type protease with grl-100-13A (a crown-like oxotricyclic core as the P2-ligand with the sulfonamide isostere as the P2' group)
5ULT: “HIV-1 wild type protease with grl-100-13A (a crown-like oxotricyclic core as the P2-ligand with the…”. X-ray diffraction, 3 ligands (8FM, NA, CL). MolNFT v1 #136207 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5ULT
- Type
- protein
- Length
- 198 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- C8B467
- Ligands
- 8FM, NA, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 99 | — | C8B467 |
Ligands and binding sites
- 8FM · (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate · ligand · chains A, B
- NA · Sodium ion · metal · chains A
- CL · Chloride ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5ULT · HIV-1 wild Type protease with GRL-100-13A (a Crown-like Oxotricyclic Core as the… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C8B467
- Elsewhere: RCSB PDB 5ULT · PDBe 5ULT · UniProt C8B467
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