UniProt C8B467
C8B467
C8B467 (UniProt C8B467): 19 experimental structures on GenesisL1, 14 ligands bound. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- C8B467
- Experimental structures
- 19
- Predicted models
- 0
- Ligands
- 14
Structures
19 records of C8B467 in the MolNFT archive: 19 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5IVT | Crystal Structure of HIV Protease complexed with [(1S)-1-[(S)-(4-chlorophenyl)-(3,5-difluorophenyl)m… | x-ray diffraction | A, B | 6EE, CL | — |
| 5IVT | Crystal structure of HIV protease complexed with [(1S)-1-[(S)-(4… | x-ray diffraction | A, B | — | — |
| 5JFP | HIV-1 wild Type protease with GRL-097-13A (a Adamantane P1-Ligand with bis-THF in P2 and… | x-ray diffraction | A, B | NA, CL, 6KK | — |
| 5JFP | HIV-1 wild type protease with grl-097-13A (a adamantane P1-ligand with bis-thf in P2 and… | x-ray diffraction | A, B | — | — |
| 5JFU | HIV-1 wild type protease with grl-007-14A (a adamantane P1-ligand with bis-thf in P2 and… | x-ray diffraction | A, B | — | — |
| 5JG1 | HIV-1 wild type protease with grl-031-14A (a adamantane P1-ligand with… | x-ray diffraction | A, B | — | — |
| 5TYR | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-121 | x-ray diffraction | A, B | 7O7 | — |
| 5TYR | X-ray crystal structure of wild type HIV-1 protease in complex with grl-121 | x-ray diffraction | A, B | 7O7 | — |
| 5TYS | X-ray crystal structure of wild type HIV-1 protease in complex with grl-142 | x-ray diffraction | A, B | 7OA | — |
| 5UFZ | HIV-1 protease complexed with inhibitor: (3R,3AS,6AR)-HEXAHYDROFURO[2, 3-B]FURAN-3-yl… | x-ray diffraction | A, B | 8BG | — |
| 5ULT | HIV-1 wild Type protease with GRL-100-13A (a Crown-like Oxotricyclic Core as the P2-Ligand with the… | x-ray diffraction | A, B | NA, CL, 8FM | — |
| 5ULT | HIV-1 wild type protease with grl-100-13A (a crown-like oxotricyclic core as the P2-ligand with the… | x-ray diffraction | A, B | NA, CL, 8FM | — |
| 5UOV | HIV-1 wild type protease with grl-1118A , an isophthalamide-derived P2-P3 ligand with the… | x-ray diffraction | A, B | 8FP, NA, CL | — |
| 5UPZ | HIV-1 wild type protease with grl-0518A , an isophthalamide-derived P2-P3 ligand with the… | x-ray diffraction | A, B | 8HD, NA, CL | — |
| 6D0D | X-ray crystal structure of wild type HIV-1 protease in complex with grl-087-13 | x-ray diffraction | A, B | FQ4 | — |
| 6D0E | X-ray crystal structure of wild type HIV-1 protease in complex with grl-084-13 | x-ray diffraction | A, B | FQ1 | — |
| 6UWB | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-08513 | x-ray diffraction | A, B | QJY | — |
| 6UWB | X-ray crystal structure of wild type HIV-1 protease in complex with grl-08513 | x-ray diffraction | A, B | QJY | — |
| 6UWC | X-ray crystal structure of wild type HIV-1 protease in complex with grl-08613 | x-ray diffraction | A, B | QK1 | — |
Ligands
- CL · Chloride ion · in 6 records
- NA · Sodium ion · in 5 records
- 7O7 · (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl {(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate · in 2 records
- 8FM · (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate · in 2 records
- QJY · (3as,4s,7ar)-hexahydro-4H-furo[2,3-b]pyran-4-yl {(2S, 3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-[(2-methylpropyl)({2-[(propan-2-yl)amino]-1,3-benzothiazol-6-yl}sulfonyl)amino]butan-2-yl}carbamate · in 2 records
- 6EE · (betaS)-4-chloro-beta-(3,5-difluorophenyl)-N-(5-fluoro-4-{2-[(2R,5S)-5-({[(2,2,2-trifluoroethyl)carbamoyl]oxy}methyl)morpholin-2-yl]ethyl}pyridin-3-yl)-L-phenylalaninamide · in 1 record
- 6KK · (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-[(3R,5R,7R)-tricyclo[3.3.1.1~3,7~]decan-1-yl]butan-2-yl}carbamate · in 1 record
- 7OA · (3s,3ar,5r,7as,8s)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate · in 1 record
- 8BG · (3r,3as,6ar)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2S)-1-(1-{[(4-aminophenyl)sulfonyl](2-methylpropyl) amino}cyclopropyl)-1-hydroxy-3-phenylpropan-2-yl]carbamate · in 1 record
- 8FP · N-[(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]-3-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidine-1-carbonyl]benzamide · in 1 record
- 8HD · N~3~-{(2S,3R)-3-hydroxy-4-[{[4-(hydroxymethyl) phenyl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}-N~1~-methyl-N~1~-[(4-methyl-1,3-oxazol-2-yl) methyl]benzene-1,3-dicarboxamide · in 1 record
- FQ1 · (3as,4s,7ar)-hexahydro-4H-furo[2,3-b]pyran-4-yl [(2S, 3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}butan-2-yl]carbamate · in 1 record
- FQ4 · (3as,4s,7ar)-hexahydro-4H-furo[2,3-b]pyran-4-yl [(2S, 3R)-1-(4-fluorophenyl)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}butan-2-yl]carbamate · in 1 record
- QK1 · (3as,4s,7ar)-hexahydro-4H-furo[2,3-b]pyran-4-yl {(2S, 3R)-1-(4-fluorophenyl)-3-hydroxy-4-[(2-methylpropyl) ({2-[(propan-2-yl)amino]-1,3-benzothiazol-6-yl}sulfonyl)amino]butan-2-yl}carbamate · in 1 record
Elsewhere
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