MolNFT v1 · #136167 · protein
The co-structure of N,N-dimethyl-4-[(6R)-6-methyl-5-(1H-PYRROLO[2,3- B]PYRIDIN-4-yl)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5- A]PYRAZIN-3- YL]BENZENESULFONAMIDE and a rationally designed PI3K-alpha mutant that mimics atr
5UKJ: “The co-structure of N,N-dimethyl-4-[(6R)-6-methyl-5-(1H-PYRROLO[2,3…”. X-ray diffraction, 1 ligand (3K6). MolNFT v1 #136167 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5UKJ
- Type
- protein
- Length
- 1,266 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P42336, P27986
- Ligands
- 3K6
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1009 | — | P42336 |
| B | — | protein | 257 | — | P27986 |
Ligands and binding sites
- 3K6 · N,N-dimethyl-4-[(6R)-6-methyl-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl]benzenesulfonamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5UKJ · The co-structure of N,N-dimethyl-4-[(6R)-6-methyl-5-(1H-pyrrolo[2,3… · the same entry in another collection · chain A against A, TM-score 1.00
- P42336 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 4,5-bisphosphate 3-kinase… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42336
- Every structure of UniProt P27986
- Elsewhere: RCSB PDB 5UKJ · PDBe 5UKJ · UniProt P42336 · UniProt P27986
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