MolNFT v1 · #136025 · protein
Protease inhibitor
5UGD · Plasminogen: “Protease inhibitor”. X-ray diffraction, 1 ligand (89S), 1 pocket (best druggability 0.39). MolNFT v1 #136025 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5UGD
- Type
- protein
- Length
- 246 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Plasminogen
- EC
- 3.4.21.7
- UniProt
- P00747
- Ligands
- 89S
- Pockets
- 1 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 10% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Plasminogen (EC 3.4.21.7) | protein | 246 | 10% helix, 35% strand | P00747 |
Ligands and binding sites
- 89S · Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(pyridin-4-yl)methyl]-L-tyrosinamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.39 | 0.81 | 16 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00747
- Elsewhere: RCSB PDB 5UGD · PDBe 5UGD · UniProt P00747
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