MolNFT v1 · #1360 · protein
NMR structure of the complex between the C32S-Y7V mutant of the NSH3 domain of GRB2 with a peptide from sos, 10 structures
1AZE: “NMR structure of the complex between the C32S-Y7V mutant of the NSH3 domain of GRB2 with a peptide from sos…”. Solution nmr. MolNFT v1 #1360 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1AZE
- Type
- protein
- Length
- 66 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GRB2; Sos
- UniProt
- P62993, P26675
Structure
solution nmr · 2 distinct chains · 0% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GRB2 | protein | 56 | 0% helix, 45% strand | P62993 |
| B | Sos | protein | 10 | 0% helix, 0% strand | P26675 |
Interfaces
1 interface between chains.
- A–B · 425 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 1AZE · NMR structure of the complex between the C32S-Y7V mutant of the NSH3 domain of GRB2 with… · the same entry in another collection · chain A against A, TM-score 1.00
- P62993 · AlphaFold monomer V2.0 prediction for growth factor receptor-bound protein 2 (P62993) · a predicted model of the same protein · chain A against A, TM-score 0.85
- P26675 · AlphaFold monomer V2.0 prediction for protein son of sevenless (P26675) · a predicted model of the same protein · chain B against A, TM-score 0.45
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62993
- Every structure of UniProt P26675
- Elsewhere: RCSB PDB 1AZE · PDBe 1AZE · UniProt P62993 · UniProt P26675
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