MolNFT v1 · #135576 · protein
Crystal structure of a mutant M. jannashii tyrosyl-tRNA synthetase
5U36 · Tyrosine--tRNA ligase: “Crystal structure of a mutant M. jannashii tyrosyl-tRNA synthetase”. X-ray diffraction, 4 pockets (best druggability 0.75). MolNFT v1 #135576 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5U36
- Type
- protein
- Length
- 588 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tyrosine--tRNA ligase
- EC
- 6.1.1.1
- UniProt
- Q57834
- Pockets
- 4 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Tyrosine--tRNA ligase (EC 6.1.1.1) | protein | 294 | 47% helix, 14% strand | Q57834 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 613 | 0.75 | 0.82 | 64 | empty |
| 2 | 658 | 0.74 | 0.81 | 68 | empty |
| 3 | 701 | 0.71 | 0.78 | 70 | empty |
| 4 | 91 | 0.41 | 0.77 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 349 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q57834
- Elsewhere: RCSB PDB 5U36 · PDBe 5U36 · UniProt Q57834
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.