MolNFT v1 · #135545 · protein
Crystal structure of mycobacterium tuberculosis dihydrofolate reductase bound to NADP and P65 inhibitor
5U27: “Crystal structure of mycobacterium tuberculosis dihydrofolate reductase bound to NADP and P65 inhibitor”. X-ray diffraction, 2 ligands (NAP, P65). MolNFT v1 #135545 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5U27
- Type
- protein
- Length
- 166 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A0A0E8UVJ4
- Ligands
- NAP, P65
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 166 | — | A0A0E8UVJ4 |
Ligands and binding sites
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · chains A
- P65 · 2,4-diamino-6-methyl-5-[3-(2,4,5-trichlorophenoxy)propyloxy]pyrimidine · ligand · chains A
- EDO · 1,2-ethanediol · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5U27 · Crystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound to NADP and… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0E8UVJ4
- Elsewhere: RCSB PDB 5U27 · PDBe 5U27 · UniProt A0A0E8UVJ4
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