MolNFT v1 · #135454 · protein

Crystal structure of S. aureus tars 1-349 in complex with udp

5TZK · Glycosyl transferase: “Crystal structure of S. aureus tars 1-349 in complex with udp”. X-ray diffraction, 3 ligands (UDP, MN, SO4), 2 pockets (best druggability 0.50). MolNFT v1 #135454 on GenesisL1: 3D structure, binding sites and…

PDB: 5TZK
Type: protein
Length: 338 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycosyl transferase
EC: 2.4.1.-
UniProt: A0A181F8T0
Ligands: UDP, MN, SO4
Pockets: 2 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
C	Glycosyl transferase (EC 2.4.1.-)	protein	338	43% helix, 18% strand	A0A181F8T0

Ligands and binding sites

UDP · Uridine-5'-diphosphate · ligand · chains C
MN · Manganese (II) ion · metal · chains C
SO4 · Sulfate ion · ion · 4 copies · chains C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	242	0.50	0.75	41	UDP, MN, SO4
2	68	0.38	0.78	14	empty

Compared structures

5TZK · Crystal structure of S. aureus TarS 1-349 in complex with UDP · the same entry in another collection · chain C against C, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A181F8T0
Elsewhere: RCSB PDB 5TZK · PDBe 5TZK · UniProt A0A181F8T0

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