MolNFT v1 · #135358 · protein + DNA
Post-catalytic nicked complex of human polymerase mu with newly incorporated UTP
5TWQ: “Post-catalytic nicked complex of human polymerase mu with newly incorporated UTP”. X-ray diffraction, 5 ligands (PPV, MN, MG). MolNFT v1 #135358 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TWQ
- Type
- protein + DNA
- Length
- 343 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9NP87
- Ligands
- PPV, MN, MG, NA, CL
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 325 | — | Q9NP87 |
| T | — | dna | 9 | — | — |
| P | — | dna | 5 | — | — |
| D | — | dna | 4 | — | — |
Ligands and binding sites
- PPV · Pyrophosphate · ligand · chains A, P
- MN · Manganese (II) ion · metal · chains A, P
- MG · Magnesium ion · metal · chains A, P
- NA · Sodium ion · metal · chains A, P
- CL · Chloride ion · ion · chains A, T
- EDO · 1,2-ethanediol · additive · 3 copies · chains A, P
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5TWQ · Post-catalytic nicked complex of human Polymerase Mu with newly incorporated UTP · the same entry in another collection · chain A against A, TM-score 1.00
- Q9NP87 · AlphaFold monomer V2.0 prediction for DNA-directed DNA/RNA polymerase mu (Q9NP87) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NP87
- Elsewhere: RCSB PDB 5TWQ · PDBe 5TWQ · UniProt Q9NP87
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