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MolNFT v1 · #135300 · protein

Crystal structure of a fragment (1-405) of an elongation factor G from vibrio vulnificus CMCP6

5TV2: “Crystal structure of a fragment (1-405) of an elongation factor G from vibrio vulnificus CMCP6”. X-ray diffraction, 6 pockets (best druggability 0.66). MolNFT v1 #135300 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5TV2
Type
protein
Length
365 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Elongation factor G
UniProt
Q8DCQ8
Pockets
6 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 33% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AElongation factor Gprotein36528% helix, 33% strandQ8DCQ8

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1600.660.9418empty
21560.570.8221empty
3580.500.8519empty
4590.460.8413empty
5850.420.7914empty

Compared structures

  • 5TV2 · Crystal structure of a fragment (1-405) of an elongation factor G from Vibrio vulnificus… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8DCQ8 · AlphaFold monomer V2.0 prediction for elongation factor G (Q8DCQ8) · a predicted model of the same protein · chain A against A, TM-score 0.97

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