MolNFT v1 · #135288 · protein
Crystal structure of a 6-cyclohexylmethyl-3-hydroxypyrimidine-2,4- dione inhibitor in complex with HIV reverse transcriptase
5TUQ: “Crystal structure of a 6-cyclohexylmethyl-3-hydroxypyrimidine-2,4- dione inhibitor in complex with HIV…”. X-ray diffraction, 2 ligands (J63, MG). MolNFT v1 #135288 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TUQ
- Type
- protein
- Length
- 960 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03366
- Ligands
- J63, MG
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 555 | — | P03366 |
| B | — | protein | 405 | — | P03366 |
Ligands and binding sites
- J63 · 1-[(benzyloxy)methyl]-6-(cyclohexylmethyl)-3-hydroxy-5-(propan-2-yl)pyrimidine-2,4(1H,3H)-dione · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5TUQ · Crystal Structure of a 6-Cyclohexylmethyl-3-hydroxypyrimidine-2,4-dione Inhibitor in… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03366
- Elsewhere: RCSB PDB 5TUQ · PDBe 5TUQ · UniProt P03366
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