MolNFT v1 · #135178 · protein
Crystal structure of a ferredoxin NADP+ reductase from neisseria gonorrhoeae with bound FAD
5TR9 · Ferredoxin-NADP reductase: “Crystal structure of a ferredoxin NADP+ reductase from neisseria gonorrhoeae with bound FAD”. X-ray diffraction, 4 ligands (FAD, NA, MG), 2 pockets (best druggability 0.74). MolNFT v1 #135178 on…
- PDB
- 5TR9
- Type
- protein
- Length
- 492 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferredoxin-NADP reductase
- UniProt
- A0A0M3GZJ1
- Ligands
- FAD, NA, MG, CL
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Ferredoxin-NADP reductase | protein | 246 | 26% helix, 35% strand | A0A0M3GZJ1 |
Ligands and binding sites
- FAD · Flavin-adenine dinucleotide · ligand · 2 copies · chains A, B
- NA · Sodium ion · metal · 2 copies · chains B
- MG · Magnesium ion · metal · chains A
- CL · Chloride ion · ion · 28 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 8 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1030 | 0.74 | 0.77 | 103 | FAD, EDO, CL |
| 2 | 51 | 0.26 | 0.73 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 833 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 5TR9 · Crystal Structure of a ferredoxin NADP+ reductase from Neisseria gonorrhoeae with bound… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0M3GZJ1
- Elsewhere: RCSB PDB 5TR9 · PDBe 5TR9 · UniProt A0A0M3GZJ1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.