MolNFT v1 · #134989 · protein
Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-naphthol 6-bisphosphonate
5TLH: “Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-naphthol…”. X-ray diffraction, 2 ligands (RD2, MDN). MolNFT v1 #134989 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TLH
- Type
- protein
- Length
- 1,394 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P00883
- Ligands
- RD2, MDN
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 350 | — | P00883 |
| B | — | protein | 349 | — | P00883 |
| C | — | protein | 351 | — | P00883 |
| D | — | protein | 344 | — | P00883 |
Ligands and binding sites
- RD2 · [(6-hydroxynaphthalen-2-yl)methylene]bis(phosphonic acid) · ligand · 4 copies · chains A, B, C, D
- MDN · Methylenediphosphonic acid · ligand · 4 copies · chains A, B, C, D
- GOL · Glycerol · additive · 2 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5TLH · Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor… · the same entry in another collection · chain D against D, TM-score 1.00
- P00883 · AlphaFold monomer V2.0 prediction for fructose-bisphosphate aldolase a (P00883) · a predicted model of the same protein · chain D against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00883
- Elsewhere: RCSB PDB 5TLH · PDBe 5TLH · UniProt P00883
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