MolNFT v1 · #134900 · protein
Crystal structure of human glycine receptor alpha-3 bound to am-3607
5TIO: “Crystal structure of human glycine receptor alpha-3 bound to am-3607”. X-ray diffraction, 3 ligands (7C6, NAG, ZN). MolNFT v1 #134900 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TIO
- Type
- protein
- Length
- 1,705 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O75311
- Ligands
- 7C6, NAG, ZN
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C, A, E | — | protein | 339 | — | O75311 |
| B | — | protein | 344 | — | O75311 |
| D | — | protein | 344 | — | O75311 |
Ligands and binding sites
- 7C6 · (3s,3as,9bs)-2-[(2H-1,3-benzodioxol-5-yl)sulfonyl]-3,5-dimethyl-1,2,3,3A,5,9B-hexahydro-4H-pyrrolo[3,4-C][1, 6]naphthyridin-4-one · ligand · 5 copies · chains C, D, A, B, E
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains C
- ZN · Zinc ion · metal · 5 copies · chains C, A, B, D, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- O75311 · AlphaFold monomer V2.0 prediction for glycine receptor subunit alpha-3 (O75311) · a predicted model of the same protein · chain C against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75311
- Elsewhere: RCSB PDB 5TIO · PDBe 5TIO · UniProt O75311
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