MolNFT v1 · #134811 · protein
1.75 a resolution structure of norovirus 3CL protease in complex with the a N-pentyl substituted macrocyclic inhibitor (17-mer)
5TG2 · 3C-like protease: “1.75 a resolution structure of norovirus 3CL protease in complex with the a N-pentyl substituted macrocyclic…”. X-ray diffraction, 1 ligand (V69). MolNFT v1 #134811 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5TG2
- Type
- protein
- Length
- 162 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3C-like protease
- EC
- 3.4.22.66
- UniProt
- Q83883
- Ligands
- V69
Structure
x-ray diffraction · 1 distinct chain · 8% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3C-like protease (EC 3.4.22.66) | protein | 162 | 8% helix, 54% strand | Q83883 |
Ligands and binding sites
- V69 · (4S,7S,17R)-7-(hydroxymethyl)-4-(2-methylpropyl)-17-pentyl-1-oxa-3,6,11-triazacycloheptadecane-2,5,10-trione · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 1 covalent (covalent ligand).
Compared structures
- 5TG2 · 1.75 A resolution structure of Norovirus 3CL protease in complex with the a n-pentyl… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q83883
- Elsewhere: RCSB PDB 5TG2 · PDBe 5TG2 · UniProt Q83883
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