MolNFT v1 · #134584 · protein
Synthesis and biological evaluation of novel selective androgen receptor modulators (sarms). part II: optimization of 4-(pyrrolidin- 1-YL)BENZONITRILE derivatives
5T8J: “Synthesis and biological evaluation of novel selective androgen receptor modulators (sarms). part II…”. X-ray diffraction, 1 ligand (77T). MolNFT v1 #134584 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5T8J
- Type
- protein
- Length
- 249 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P10275
- Ligands
- 77T
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 249 | — | P10275 |
Ligands and binding sites
- 77T · 2-fluoro-4-[(2S,3S)-3-hydroxy-2,3-dimethylpyrrolidin-1-yl]-3-methylbenzonitrile · ligand · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P10275 · AlphaFold monomer V2.0 prediction for androgen receptor (P10275) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10275
- Elsewhere: RCSB PDB 5T8J · PDBe 5T8J · UniProt P10275
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