MolNFT v1 · #134499 · protein

High resolution structure of mouse cryptochrome 1

5T5X · Cryptochrome-1: “High resolution structure of mouse cryptochrome 1”. X-ray diffraction, 1 ligand (CL), 4 pockets (best druggability 0.73). MolNFT v1 #134499 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5T5X
Type: protein
Length: 470 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cryptochrome-1
UniProt: P97784
Ligands: CL
Pockets: 4 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cryptochrome-1	protein	470	49% helix, 7% strand	P97784

Ligands and binding sites

CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	675	0.73	0.79	57	empty
2	391	0.65	0.78	36	empty
3	98	0.35	0.73	21	empty
4	56	0.32	0.77	14	empty

Compared structures

5T5X · High resolution structure of mouse Cryptochrome 1 · the same entry in another collection · chain A against A, TM-score 1.00
P97784 · AlphaFold monomer V2.0 prediction for cryptochrome-1 (P97784) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P97784
Elsewhere: RCSB PDB 5T5X · PDBe 5T5X · UniProt P97784

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