MolNFT v1 · #134377 · protein

MPI3KD in complex with 5E

5T2B: “MPI3KD in complex with 5E”. X-ray diffraction, 1 ligand (74O). MolNFT v1 #134377 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5T2B
Type: protein
Length: 820 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O35904
Ligands: 74O

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	820	—	O35904

Ligands and binding sites

74O · 5-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]-3-(1~{H}-pyrazol-4-yl)pyrazin-2-amine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5T2B · mPI3Kd IN COMPLEX WITH 5e · the same entry in another collection · chain A against A, TM-score 1.00
O35904 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 4,5-bisphosphate 3-kinase… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O35904
Elsewhere: RCSB PDB 5T2B · PDBe 5T2B · UniProt O35904

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