MolNFT v1 · #1336 · protein
Inhibitor-free catalytic fragment of human fibroblast collagenase, NMR, 30 structures
1AYK: “Inhibitor-free catalytic fragment of human fibroblast collagenase, NMR, 30 structures”. Solution nmr, 2 ligands (ZN, CA), 2 pockets (best druggability 0.48). MolNFT v1 #1336 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1AYK
- Type
- protein
- Length
- 169 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Collagenase
- EC
- 3.4.24.7
- UniProt
- P03956
- Ligands
- ZN, CA
- Pockets
- 2 · best druggability 0.48
Structure
solution nmr · 1 distinct chain · 23% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Collagenase (EC 3.4.24.7) | protein | 169 | 23% helix, 15% strand | P03956 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 148 | 0.48 | 0.78 | 18 | empty |
| 2 | 74 | 0.34 | 0.76 | 15 | empty |
Compared structures
- 1AYK · Inhibitor-free catalytic fragment of human fibroblast collagenase, NMR, 30 structures · the same entry in another collection · chain A against A, TM-score 1.00
- P03956 · AlphaFold monomer V2.0 prediction for interstitial collagenase (P03956) · a predicted model of the same protein · chain A against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03956
- Elsewhere: RCSB PDB 1AYK · PDBe 1AYK · UniProt P03956
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.