MolNFT v1 · #13054 · protein
Integral membrane peripheral light harvesting complex from rhodopseudomonas acidophila strain 10050
1KZU · Light harvesting protein B-800/850: “Integral membrane peripheral light harvesting complex from rhodopseudomonas acidophila strain 10050”. X-ray diffraction, 2 ligands (BCL, RG1), 6 pockets (best druggability 0.63). MolNFT v1 #13054…
- PDB
- 1KZU
- Type
- protein
- Length
- 270 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Light harvesting protein B-800/850
- UniProt
- P26789, P26790
- Ligands
- BCL, RG1
- Pockets
- 6 · best druggability 0.63
Structure
x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D, G | Light harvesting protein B-800/850 | protein | 49 | 76% helix, 0% strand | P26789 |
| B, E, H | Light harvesting protein B-800/850 | protein | 41 | 78% helix, 0% strand | P26790 |
Ligands and binding sites
- BCL · Bacteriochlorophyll A · ligand · 9 copies · chains A, B, D, E, G, H
- RG1 · Rhodopin b-D-glucoside · ligand · 6 copies · chains A, B, D, E, G, H
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 456 | 0.63 | 0.76 | 35 | RG1 |
| 2 | 479 | 0.62 | 0.75 | 36 | RG1 |
| 3 | 251 | 0.53 | 0.75 | 24 | empty |
| 4 | 173 | 0.45 | 0.74 | 16 | empty |
| 5 | 94 | 0.39 | 0.75 | 14 | empty |
Interfaces
9 interfaces between chains.
- G–H · 681 Ų buried · 6 hydrogen bonds · protein-protein
- D–E · 679 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 677 Ų buried · 6 hydrogen bonds · protein-protein
- D–G · 490 Ų buried · 4 hydrogen bonds · protein-protein
- A–D · 488 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 modified (formylation).
Compared structures
- 1KZU · Integral membrane peripheral light harvesting complex from rhodopseudomonas acidophila… · the same entry in another collection · chain H against H, TM-score 1.00
- P26789 · AlphaFold monomer V2.0 prediction for light-harvesting protein B-800/850 alpha chain… · a predicted model of the same protein · chain A against A, TM-score 0.89
- P26790 · AlphaFold monomer V2.0 prediction for light-harvesting protein B-800/850 beta chain… · a predicted model of the same protein · chain B against A, TM-score 0.78
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P26789
- Every structure of UniProt P26790
- Elsewhere: RCSB PDB 1KZU · PDBe 1KZU · UniProt P26789 · UniProt P26790
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