MolNFT v1 · #129852 · protein

Human STK10 bound to dovitinib

5OWQ: “Human STK10 bound to dovitinib”. X-ray diffraction, 1 ligand (38O). MolNFT v1 #129852 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5OWQ
Type: protein
Length: 509 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O94804
Ligands: 38O

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	255	—	O94804
B	—	protein	254	—	O94804

Ligands and binding sites

38O · 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5OWQ · Human STK10 bound to dovitinib · the same entry in another collection · chain A against A, TM-score 1.00
O94804 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase 10 (O94804) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O94804
Elsewhere: RCSB PDB 5OWQ · PDBe 5OWQ · UniProt O94804

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