MolNFT v1 · #129826 · protein
Crystal structure of an electron transfer flavoprotein from geobacter metallireducens
5OW0 · Electron transfer flavoprotein, beta subunit: “Crystal structure of an electron transfer flavoprotein from geobacter metallireducens”. X-ray diffraction, 2 ligands (AMP, FAD), 6 pockets (best druggability 0.77). MolNFT v1 #129826 on…
- PDB
- 5OW0
- Type
- protein
- Length
- 543 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Electron transfer flavoprotein, beta subunit; Electron transfer flavoprotein, alpha…
- UniProt
- Q39VG5, Q39VG4
- Ligands
- AMP, FAD
- Pockets
- 6 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Electron transfer flavoprotein, beta subunit | protein | 251 | 31% helix, 31% strand | Q39VG5 |
| A | Electron transfer flavoprotein, alpha subunit | protein | 292 | 29% helix, 28% strand | Q39VG4 |
Ligands and binding sites
- AMP · Adenosine monophosphate · ligand · chains B
- FAD · Flavin-adenine dinucleotide · ligand · chains B, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 622 | 0.77 | 0.83 | 73 | empty |
| 2 | 244 | 0.76 | 0.89 | 42 | AMP |
| 3 | 301 | 0.66 | 0.82 | 42 | FAD |
| 4 | 159 | 0.57 | 0.82 | 22 | empty |
| 5 | 97 | 0.56 | 0.85 | 18 | empty |
Interfaces
1 interface between chains.
- B–A · 3596 Ų buried · 59 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 modified (engineered).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q39VG5
- Every structure of UniProt Q39VG4
- Elsewhere: RCSB PDB 5OW0 · PDBe 5OW0 · UniProt Q39VG5 · UniProt Q39VG4
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