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MolNFT v1 · #129579 · protein

Human biliverdin IX beta reductase: NADP/ERYTHROSIN extra bluish ternary complex

5OOH · Flavin reductase (NADPH): “Human biliverdin IX beta reductase: NADP/ERYTHROSIN extra bluish ternary complex”. X-ray diffraction, 2 ligands (NAP, 9ZZ), 1 pocket (best druggability 0.73). MolNFT v1 #129579 on GenesisL1: 3D structure…

PDB
5OOH
Type
protein
Length
205 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Flavin reductase (NADPH)
EC
1.5.1.30, 1.3.1.24
UniProt
P30043
Ligands
NAP, 9ZZ
Pockets
1 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 21% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AFlavin reductase (NADPH) (EC 1.5.1.30, 1.3.1.24)protein20536% helix, 21% strandP30043

Ligands and binding sites

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · chains A
  • 9ZZ · Erythrosin · ligand · chains A
  • GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15050.730.8244NAP, 9ZZ

Compared structures

  • 5OOH · Human biliverdin IX beta reductase: NADP/Erythrosin extra bluish ternary complex · the same entry in another collection · chain A against A, TM-score 1.00
  • P30043 · AlphaFold monomer V2.0 prediction for flavin reductase (NADPH) (P30043) · a predicted model of the same protein · chain A against A, TM-score 0.99

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