MolNFT v1 · #129329 · protein
Cereblon isoform 4 from magnetospirillum gryphiswaldense in complex with aminoglutethimide
5OH1: “Cereblon isoform 4 from magnetospirillum gryphiswaldense in complex with aminoglutethimide”. X-ray diffraction, 3 ligands (EF2, 9UQ, ZN). MolNFT v1 #129329 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5OH1
- Type
- protein
- Length
- 309 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A4TVL0
- Ligands
- EF2, 9UQ, ZN
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 105 | — | A4TVL0 |
| B | — | protein | 104 | — | A4TVL0 |
| C | — | protein | 100 | — | A4TVL0 |
Ligands and binding sites
- EF2 · S-Thalidomide · ligand · 2 copies · chains A, B
- 9UQ · (3~{R})-3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione · ligand · chains C
- ZN · Zinc ion · metal · 3 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5OH1 · Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Aminoglutethimide · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A4TVL0
- Elsewhere: RCSB PDB 5OH1 · PDBe 5OH1 · UniProt A4TVL0
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