MolNFT v1 · #129116 · protein
Penicillin-binding protein 2X (PBP2X) from streptococcus pneumoniae
5OAU: “Penicillin-binding protein 2X (PBP2X) from streptococcus pneumoniae”. X-ray diffraction, 9 pockets (best druggability 0.77). MolNFT v1 #129116 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5OAU
- Type
- protein
- Length
- 667 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Penicillin-binding protein 2X
- UniProt
- P59676
- Pockets
- 9 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Penicillin-binding protein 2X | protein | 667 | 29% helix, 26% strand | P59676 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 390 | 0.77 | 0.87 | 54 | empty |
| 2 | 393 | 0.64 | 0.78 | 40 | empty |
| 3 | 100 | 0.57 | 0.86 | 21 | empty |
| 4 | 183 | 0.46 | 0.75 | 26 | empty |
| 5 | 84 | 0.44 | 0.80 | 18 | empty |
Compared structures
- 5OAU · Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae · the same entry in another collection · chain A against A, TM-score 1.00
- P59676 · AlphaFold monomer V2.0 prediction for penicillin-binding protein 2X (P59676) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P59676
- Elsewhere: RCSB PDB 5OAU · PDBe 5OAU · UniProt P59676
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