UniProt P59676
Penicillin-binding protein 2X (P59676)
Penicillin-binding protein 2X (UniProt P59676): 18 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P59676
- Protein
- Penicillin-binding protein 2X
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 23 · 3 records with a druggable one
Structures
19 records of P59676 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PYY | Double mutant PBP2x T338A/M339F from Streptococcus pneumoniae strain R6 at 2.4 A resolution | x-ray diffraction | A | — | — |
| 1PYY | Double mutant PBP2X T338A/M339F from streptococcus pneumoniae strain R6 at 2.4 a resolution | x-ray diffraction | A | — | — |
| 2Z2L | Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2Z2L | Penicillin-binding protein 2X (PBP2X) from streptococcus pneumoniae | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2Z2M | Cefditoren-Acylated Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2Z2M | Cefditoren-acylated penicillin-binding protein 2X (PBP2X) from streptococcus pneumoniae | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2ZC3 | Penicillin-binding protein 2X (PBP 2X) acyl-enzyme complex (biapenem) from Streptococcus pneumoniae | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2ZC3 | Penicillin-binding protein 2X (pbp 2X) acyl-enzyme complex (biapenem) from streptococcus pneumoniae | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2ZC4 | Penicillin-binding protein 2X (PBP 2X) acyl-enzyme complex (tebipenem) from Streptococcus pneumoniae | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2ZC4 | Penicillin-binding protein 2X (pbp 2X) acyl-enzyme complex (tebipenem) from streptococcus pneumoniae | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5OAU | Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae | x-ray diffraction | A | — | — |
| 5OAU | Penicillin-binding protein 2X (PBP2X) from streptococcus pneumoniae | x-ray diffraction | A | — | — |
| 5OIZ | Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae in complex with oxacillin | x-ray diffraction | A | — | — |
| 5OIZ | Penicillin-binding protein 2X (PBP2X) from streptococcus pneumoniae in complex with oxacillin | x-ray diffraction | A | — | — |
| 5OJ0 | Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae in complex with Cefepime | x-ray diffraction | A | 9WT | 8 (best 0.74) |
| 5OJ0 | Penicillin-binding protein 2X (PBP2X) from streptococcus pneumoniae in complex with cefepime | x-ray diffraction | A | 9WT | — |
| 5OJ1 | Penicillin Binding Protein 2x (PBP2x) from S.pneumoniae in complex with Oxacillin and a… | x-ray diffraction | A | 1S6, NA | 7 (best 0.74) |
| 5OJ1 | Penicillin binding protein 2X (PBP2X) from S.PNEUMONIAE in complex with oxacillin and a… | x-ray diffraction | A | NA | — |
| P59676 | AlphaFold monomer V2.0 prediction for penicillin-binding protein 2X (P59676) | predicted | A | — | 8 (best 0.73) |
Ligands
Experiment against prediction
- 2Z2L chain B against the predicted model P59676: TM-score 0.99, RMSD 0.50 Å
- 2Z2L chain B against the predicted model P59676: TM-score 0.99, RMSD 0.50 Å
- 2ZC4 chain B against the predicted model P59676: TM-score 0.99, RMSD 0.51 Å
- 2ZC4 chain B against the predicted model P59676: TM-score 0.99, RMSD 0.51 Å
- 2ZC3 chain B against the predicted model P59676: TM-score 0.99, RMSD 0.53 Å
- 2ZC3 chain B against the predicted model P59676: TM-score 0.99, RMSD 0.53 Å
- 2Z2M chain C against the predicted model P59676: TM-score 0.99, RMSD 0.40 Å
- 2Z2M chain C against the predicted model P59676: TM-score 0.99, RMSD 0.40 Å
- 2ZC3 chain C against the predicted model P59676: TM-score 0.99, RMSD 0.41 Å
- 2ZC3 chain C against the predicted model P59676: TM-score 0.99, RMSD 0.41 Å
Elsewhere
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