MolNFT v1 · #129105 · protein
Crystal structure of mutant achbp in complex with tropisetron (T53F, Q74R, Y110A, I135S, G162E)
5OAJ: “Crystal structure of mutant achbp in complex with tropisetron (T53F, Q74R, Y110A, I135S, G162E)”. X-ray diffraction, 2 ligands (TKT, NAG). MolNFT v1 #129105 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5OAJ
- Type
- protein
- Length
- 2,080 residues
- Chains
- 10
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8WSF8
- Ligands
- TKT, NAG
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D, E, F, H, I | — | protein | 206 | — | Q8WSF8 |
| B | — | protein | 221 | — | Q8WSF8 |
| C, G | — | protein | 205 | — | Q8WSF8 |
| J | — | protein | 213 | — | Q8WSF8 |
Ligands and binding sites
- TKT · (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate · ligand · 2 copies · chains D, E, F, J
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A, E, J, H, I
- EDO · 1,2-ethanediol · additive · 42 copies · chains A, B, C, D, E, F, G, J, H, I
- FLC · Citrate anion · additive · 3 copies · chains C, D, G, H, I
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WSF8
- Elsewhere: RCSB PDB 5OAJ · PDBe 5OAJ · UniProt Q8WSF8
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