MolNFT v1 · #128654 · protein

Crystal structure of neanderthal adenylosuccinate lyase (ADSL)IN complex with its products aicar and fumarate

5NXA: “Crystal structure of neanderthal adenylosuccinate lyase (ADSL)IN complex with its products aicar and fumarate”. X-ray diffraction, 4 ligands (SSS, FUM, AMZ). MolNFT v1 #128654 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 5NXA
Type: protein
Length: 3,609 residues
Chains: 8
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Ligands: SSS, FUM, AMZ, CL

Structure

x-ray diffraction · 8 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	464	—	—
B	—	protein	415	—	—
C	—	protein	418	—	—
D	—	protein	440	—	—
E	—	protein	466	—	—
F	—	protein	466	—	—
G	—	protein	463	—	—
H	—	protein	477	—	—

Ligands and binding sites

SSS · N-{[5-amino-1-(5-O-phosphono-beta-D-arabinofuranosyl)-1H-imidazol-4-yl]carbonyl}-L-aspartic acid · ligand · 6 copies · chains A, B, D, C, E, F, G, H
FUM · Fumaric acid · ligand · 2 copies · chains B, C, D, E, G, H
AMZ · Aminoimidazole 4-carboxamide ribonucleotide · ligand · 2 copies · chains B, C, D, E, G, H
CL · Chloride ion · ion · 8 copies · chains A, B, C, D, E, F, G, H

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5NXA · Crystal structure of Neanderthal Adenylosuccinate Lyase (ADSL)in complex with its… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 5NXA · PDBe 5NXA

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