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Ligand · AMZ

AMZ · Aminoimidazole 4-carboxamide ribonucleotide

AMZ, Aminoimidazole 4-carboxamide ribonucleotide (C9 H15 N4 O8 P, 338.2 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (9 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
AMZ
Formula
C9 H15 N4 O8 P
Class
ligand
Structures
12
PDB entries
9

Binding sites

AMZ in 12 structures; the first of them:

  • 4XWF · Crystal structure of the ZMP riboswitch at 1.80 angstrom · AMZ A101 · binds U11, G12, A28, C29
  • 4ZNP · The structure of A pfI Riboswitch Bound to ZMP · AMZ A101 · binds U13, G14, A30, C31, G59, A60, C65, U66 and 1 more
  • 5DN1 · Crystal structure of Phosphoribosyl isomerase A from Streptomyces coelicolor · AMZ A304 · binds LEU20, GLY23, VAL52, LEU54, ALA57, PHE58, SER81, GLY82 and 9 more
  • 5NXA · Crystal structure of Neanderthal Adenylosuccinate Lyase (ADSL)in complex with its… · AMZ C502 · binds ARG20, TYR21, GLY288, MET299, ARG303, GLU81, ARG85, HIS86 and 10 more
  • 5PZW · Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase… · AMZ A402 · binds VAL17, GLU20, GLY21, ALA24, GLY26, THR27, GLY28, GLU29 and 7 more
  • 5UZ0 · Crystal structure of AICARFT bound to an antifolate · AMZ A601 · binds ASN431, ARG451, ALA540, PHE541, ARG588, PHE590, ARG207, TYR208 and 6 more
  • 9BZC · Cocrystal structure of Clostridium beijerinckii ZTP riboswitch with ZMP and Cs · AMZ A105 · binds C12, U13, G14, A29, C30, G78, C84, U85 and 1 more
  • 5NXA · Crystal structure of neanderthal adenylosuccinate lyase (ADSL)IN complex with its… · AMZ C502 · binds ARG20, TYR21, GLY288, MET299, ARG303, ARG85, HIS86, ASP87 and 9 more
  • 5PZW · Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase… · AMZ A402 · binds VAL17, GLU20, ALA24, THR27, GLY28, GLU29, LEU30, THR31 and 4 more
  • 5UY8 · Crystal structure of aicarft bound to an antifolate · AMZ A602 · binds ASN431, ARG451, ALA540, PHE541, ARG588, PHE590, ARG207, TYR208 and 6 more
  • 5UZ0 · Crystal structure of aicarft bound to an antifolate · AMZ A601 · binds ASN431, ARG451, ALA540, PHE541, ARG588, PHE590, ARG207, TYR208 and 6 more
  • 6OD9 · Co-crystal structure of the fusobacterium ulcerans ztp riboswitch using an X-ray… · AMZ A102 · binds U16, G17, A34, C35, G63, C69, U70, G71

Residues it binds most

GLY 30, ARG 30, SER 14, ASN 22, LYS 25, TYR 29, LEU 18, THR 14, ASP 26, VAL 15 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • 8US · N-(6-fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide
  • 94J · N,N'-(pentane-1,5-diyldicarbamoyl)bis(3-chlorobenzene-1-sulfonamide)
  • FUM · Fumaric acid
  • SSS · N-{[5-amino-1-(5-O-phosphono-beta-D-arabinofuranosyl)-1H-imidazol-4-yl]carbonyl}-L-aspartic acid
  • CS · Cesium ion
  • K · Potassium ion
  • CL · Chloride ion
  • 8UM · 5-[(5S)-5-ethyl-5-methyl-6-oxo-1,4,5,6-tetrahydropyridin-3-yl]-N-(6-fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)thiophene-2-sulfonamide
  • IRI · Iridium hexammine ion
  • SO4 · Sulfate ion
  • CAC · Cacodylate ion

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